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HRID969931

反应详情

EQUATION

反应方程式

HRID 969931 的结构方程式

REACTANTS

反应物

3
结构：Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]1O
HCID5957

Adenosine triphosphate

C10H16N5O13P3

结构：CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)[O-]
HCID167945

Pantothenate

C9H16NO5-

结构：CC(C)(COP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)N[C@@H](CS)C(=O)O
HCID440304

Pantothenylcysteine 4'-phosphate

C12H23N2O9PS

PRODUCTS

生成物

3
结构：CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1OP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCS
HCID87642

Coenzyme A

C21H36N7O16P3S

结构：CC(C)(COP(=O)(O)O)[C@@H](O)C(=O)NCCC(=O)NCCS
HCID115254

(3R)-3-Hydroxy-2,2-dimethyl-4-oxo-4-({3-oxo-3-[(2-sulfanylethyl)amino]propyl}amino)butyl dihydrogen phosphate

C11H23N2O7PS

结构：CC(C)(COP(=O)(O)OP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O)[C@@H](O)C(=O)NCCC(=O)NCCS
HCID444485

Dephospho-CoA

C21H35N7O13P2S

PROCEDURE

实验过程

Production cells used to produce pantothenate and/or CoA, can be used to express alpha-ketopantoate hydroxymethyltransferase (E.C. 2.1.2.11), alpha-ketopantoate reductase (E.C. 1.1.1.169), and pantothenate synthase (E.C. 6.3.2.1), to produce pantothenate, or in addition pantothenate kinase (E.C. 2.7.1.33), 4′-phosphopantethenoyl-1-cysteine synthetase (E.C. 6.3.2.5), 4′-phosphopantothenoylcysteine decarboxylase (E.C. 4.1.1.36), ATP:4′-phosphopantetheine adenyltransferase (E.C. 2.7.7.3), and dephospho-CoA kinase (E.C. 2.7.1.24), to produce coenzyme A.