HCID 22935209, compound → HCID 69410690, compound

Participants

Reaction Conditions

Reaction Steps

To 25.8 g (80 mmol) of 2-[2-(4-bromophenyl)ethyl]-3-fluorobenzoic acid was added 550 g of polyphosphoric acid, and the mixture was stirred at 170° C. for 3 hours. After cooling the mixture to 80° C. by allowing to stand, water was added to the mixture and the resulting mixture was cooled to room temperature under stirring by allowing to stand.

Provenance & Evidence