Triphenylphosphine → HCID 86594264, compound

HRID 970053Notes

Reaction equation

HRID 970053 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][CH:9]=[C:8]([CH2:12][Br:13])[C:3]=1[C:4]([O:6][CH3:7])=[O:5].[C:14]1([P:20]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>C(#N)C>[Br-:13].[Cl:1][C:2]1[C:3]([C:4]([O:6][CH3:7])=[O:5])=[C:8]([CH:9]=[CH:10][CH:11]=1)[CH2:12][P+:20]([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 22935208Methyl 2-(bromomethyl)-6-chlorobenzoate

Product 1

HCID 86594264HCID 86594264, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
80 °C

Procedure

To a mixture of 27.6 g of methyl 2-chloro-6-bromomethylbenzoate and 39.0 g of triphenylphosphine was added 200 ml of acetonitrile, and the mixture was stirred at 80° C. for 3 hours.

Sources & evidence

ORD record
ord-9a76204ad2aa4a6b812f77de1804966c
Source dataset
uspto-grants-2007_12
Patent number
US07309718B2

Reaction notes

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