HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 11539546, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 3-(4-benzyloxyphenyl)-2-chloropropanoate | HCID 10780869 | — |
| Reactant | HCID 178527853 | HCID 178527853 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11539546 | HCID 11539546 | — |
Reaction Steps
The solution of 0.3 g (0.001 mol) of methyl3-[4-(Benzyloxy)phenyl]-2-chloropropionate in methanol (2 ml) was added dropwise to the solution of 0.18 g (0.001 mol) 5-phenyl-1H-imidazol-2-thiol and 0.04 g (0.001 mol) of NaOH in methanol (3 ml). The solution then was heated at reflux for 5 h. The crude product obtained after removing the solvent was used without purification in the next step of the synthesis.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07309791B2 |
| Source dataset | uspto-grants-2007_12 |
| ORD ID | ord-35fa3076f9d24abf83425c9fcf2cf3a2 |
| Source note | uspto-grants-2007_12 |