Sodium Hydroxide → HCID 69406753, compound

HRID 970953Notes

Reaction equation

HRID 970953 reaction equation
C[C:2]12[C:21]3(C)[N:6]4[CH2:7][CH2:8][CH2:9][N:10]3[CH2:11][CH2:12][N:13]1[CH2:14][CH:15]([CH:16]([O:19][CH3:20])[CH:17]=[CH2:18])[N:3]2CC4.[OH-].[Na+]>O>[NH:6]1[CH2:7][CH2:8][CH2:9][NH:10][CH2:11][CH2:12][NH:13][CH2:14][CH:15]([CH:16]([O:19][CH3:20])[CH:17]=[CH2:18])[NH:3][CH2:2][CH2:21]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 69408191HCID 69408191, compound

Product 1

HCID 69406753HCID 69406753, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

This product is obtained according to a procedure identical to that described in example B from 0.8 g (2.61 mmol) of compound 17. Compound 18·4HCl is isolated in the form of an off-white powder. This powder is dissolved in the minimum amount of water and the solution is brought to basic pH by addition of NaOH pellets. After extraction with 3×100 ml of chloroform and drying over MgSO4, the solvents are evaporated.

Workup

  1. customThis product is obtained
  2. customis isolated in the form of an off-white powder
  3. extractionAfter extraction with 3×100 ml of chloroform
  4. dry with materialdrying over MgSO4
  5. customthe solvents are evaporated

Sources & evidence

ORD record
ord-450cf6ed6d08457aac53eb3d1abd7dcd
Source dataset
uspto-grants-2007_12
Patent number
US07312327B2

Reaction notes

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