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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 971071Generated: October 25, 2026

Methyl 3-formyl-1H-indole-7-carboxylate → Methyl 3-(hydroxyiminomethyl)indole-7-carboxylate

https://huagongshe.com/reaction/971071

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-formyl-1H-indole-7-carboxylateHCID 762965—
ReactantHydroxyammonium hydrochlorideHCID 22029257—
SolventDimethylformamideHCID 6228—
ProductMethyl 3-(hydroxyiminomethyl)indole-7-carboxylateHCID 13637638997.4%

Reaction Steps

5 g of methyl 3-formylindole-7-carboxylate (0.024 mol) are added to a solution of 0.03 mol of hydroxylammonium hydrochloride in dimethylformamide. The reaction mixture is heated at 125° for one hour and subjected to conventional work-up, giving 5.1 g of methyl 3-(hydroxyiminomethyl)indole-7-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07312342B2
Source datasetuspto-grants-2007_12
ORD IDord-35682b06232f4d1fb4ecb9fe1e25772f
Source noteuspto-grants-2007_12