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HRID971071

反应详情

EQUATION

反应方程式

HRID 971071 的结构方程式

REACTANTS

反应物

2
结构：COC(=O)c1cccc2c(C=O)c[nH]c12
HCID762965

Methyl 3-formyl-1H-indole-7-carboxylate

C11H9NO3

结构：Cl.[NH3+]O
HCID22029257

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1cccc2c(C=NO)c[nH]c12
HCID136376389

未命名化合物

收率 97.4%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

5 g of methyl 3-formylindole-7-carboxylate (0.024 mol) are added to a solution of 0.03 mol of hydroxylammonium hydrochloride in dimethylformamide. The reaction mixture is heated at 125° for one hour and subjected to conventional work-up, giving 5.1 g of methyl 3-(hydroxyiminomethyl)indole-7-carboxylate.

WORKUP

后处理

  1. temperatureThe reaction mixture is heated at 125° for one hour