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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 971168Generated: October 30, 2026

Tetrahydrofuran → HCID 59019996, compound

https://huagongshe.com/reaction/971168

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 59020235HCID 59020235—
SolventHydrochloric AcidHCID 313—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 59019996HCID 59019996—

Reaction Steps

A solution of the product from Example 197 (15.0 mg, 0.028 mmol) in 5 ml of 4N HCl in dioxane and 0.5 mL of THF was refluxed for 6 hr. The mixture was cooled to rt and purified with reverse phase HPLC to give the desired product as white solid. MS found: (M+1)+=509.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07312214B2
Source datasetuspto-grants-2007_12
ORD IDord-be75cf8759fc47b4bf42f542e8ab2aec
Source noteuspto-grants-2007_12