Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Morpholine → HCID 14547438, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Morpholine | HCID 8083 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Chloroacetamidine monohydrochloride | HCID 2776957 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 14547438 | HCID 14547438 | — |
반응 단계
Sodium hydride (2.4 g, 60 mmol, 60%) was added to a solution of morpholine (5.2 g, 60 mmol) in THF (40 mL, anhydrous) and stirred for 30 min at room temperature under nitrogen. Chloroacetamidine hydrochloride (2.58 g, 20 mmol) was added to this solution in one portion and stirred at 50° C. overnight. Solvent was removed under reduced pressure and the dark brown oily residue was directly used in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07312330B2 |
| 출처 데이터셋 | uspto-grants-2007_12 |
| ORD ID | ord-7cf2c5a69a3d4e238f1b207eb22ecc43 |
| 출처 메모 | uspto-grants-2007_12 |