HCID 59021554, compound → HCID 59021465, compound

Participants

Reaction Steps

A catalytic amount palladium hydroxide on carbon powder (20% Pd moisture ea. 60%) was added to a solution of N-(4-tert-butylphenyl)-7-benzyl-5,6,7,8-tetrahydro-2-(morpholinomethyl)pyrido[3,4-d]pyrimidin-4-amine (240 mg, 0.51 mmol) in methanol and was stirred under a hydrogen filled balloon over night at room temperature. Reaction solution was filtered through celite and filtrate was concentrated to yield the product as a white powder (150 mg).

Provenance & Evidence