HCID 21313745, compound → HCID 21313752, compound

Participants

Reaction Steps

In the preparation of the 3-acetamido-2,4,6-triiodo-5-trishydroxymethylacetamido-benzoic acid of the invention, 3-nitro-trishydroxymethylacetamido-benzoic acid is reduced to form 3-amino-5-trishydroxymethylacetamido-benzoic acid. The latter is then iodinated to form 3-amino-2,4,6-triiodo-5-trishydroxymethylacetamidobenzoic acid, after which the 3-amino compound is acylated to form the desired 3-acetamido-2,4,6-triiodo-5-trishydroxymethylacetamido-benzoic acid.

Provenance & Evidence