Acetyl chloride → HCID 21314106, compound

HRID 971450Notes

Reaction equation

HRID 971450 reaction equation
C(N(CC)CC)C.[C:8](Cl)(=[O:10])[CH3:9].[CH2:12]([O:21][C:22](=[O:25])[NH:23][OH:24])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]>CCOCC>[CH2:12]([O:21][C:22](=[O:25])[NH:23][O:24][C:8](=[O:10])[CH3:9])[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20]

Participants

5

Reactant 3

HCID 6367Acetyl chlorideHCID 8471TriethylamineHCID 21314104Nonyl hydroxycarbamate

Product 1

HCID 21314106HCID 21314106, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

25 Parts of triethylamine are added over 30 minutes to a stirred solution of 19.6 parts of acetyl chloride and 50.6 parts of nonyl-N-hydroxycarbamate in 500 parts of ether at 0°-5° C. keeping the pH of the mixture in the range pH3 to pH6. The reaction is stirred for a further 2 hours at 0°-5° C. followed by 24 hours at 25° C. and is then filtered to remove amine hydrochloride. The filtrates are washed with water, dried, filtered and evaporated to constant weight at 30° C. under reduced pressure to give 61 parts of nonyl-N-(acetoxy)carbamate as a pale yellow oil.

Workup

  1. waitfollowed by 24 hours at 25° C.
  2. filtrationis then filtered
  3. customto remove amine hydrochloride
  4. washThe filtrates are washed with water
  5. customdried
  6. filtrationfiltered
  7. customevaporated to constant weight at 30° C. under reduced pressure

Sources & evidence

ORD record
ord-d93cfdf3b6dc41fb85f7c90fb31d0634
Source dataset
uspto-grants-1979_07
Patent number
US04160077

Reaction notes

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