HCID 12278206, compound → HCID 178506831, compound

HRID 971495Notes

Reaction equation

HRID 971495 reaction equation
C([Li:5])CCC.[CH2:6]([C:8]1[CH:17]=[CH:16][C:15]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]=2[N:9]=1)[CH3:7]>>[CH2:6]([C:8]1[CH:17]=[CH:16][C:15]2[CH2:14][CH2:13][CH2:12][CH:11]([Li:5])[C:10]=2[N:9]=1)[CH3:7]

Participants

3

Reactant 2

HCID 12278206HCID 12278206, compoundHCID 178418339Butyllithium

Product 1

HCID 178506831HCID 178506831, compound

Procedure

By the method described in Example 7 using n-butyl lithium solution (9% w/v, 10 ml, 0.014 mol), and 2-ethyl-5,6,7,8-tetrahydroquinoline (2.3 g, 0.014 mol) and title compound is prepared and converted in situ to methyl 2-ethyl-5,6,7,8-tetrahydroquinoline-8-carboxylate which was converted to the corresponding 8-thioamide by the procedure described in U.S. Ser. No. 460,265.

Sources & evidence

ORD record
ord-6758861bd91c4bdb94082602032be8c9
Source dataset
uspto-grants-1979_07
Patent number
US04160094

Reaction notes

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