HCID 12278207, compound → HCID 178506830, compound

HRID 971496Notes

Reaction equation

HRID 971496 reaction equation
C([Li:5])CCC.[CH2:6]([C:10]1[CH:19]=[CH:18][C:17]2[CH2:16][CH2:15][CH2:14][CH2:13][C:12]=2[N:11]=1)[CH2:7][CH2:8][CH3:9]>>[CH2:6]([C:10]1[CH:19]=[CH:18][C:17]2[CH2:16][CH2:15][CH2:14][CH:13]([Li:5])[C:12]=2[N:11]=1)[CH2:7][CH2:8][CH3:9]

Participants

3

Reactant 2

HCID 12278207HCID 12278207, compoundHCID 178418339Butyllithium

Product 1

HCID 178506830HCID 178506830, compound

Procedure

By the method described in Example 7 using n-butyl lithium solution (9% w/v, 13.5 g, 0.03 mol) and 2-n-butyl-5,6,7,8-tetrahydroquinoline (6 g., 0.03 mol) the title compound is prepared and converted in situ to methyl 2-n-butyl-5,6,7,8-tetrahydroquinoline-8-carboxylate and then to the corresponding 8-thioamide by the procedure described in U.S. Ser. No. 460,265.

Sources & evidence

ORD record
ord-f8d2f10860d349b7aa59bf5421520b6e
Source dataset
uspto-grants-1979_07
Patent number
US04160094

Reaction notes

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