Quinoline, 5,6,7,8-tetrahydro-3,4-dimethyl- → HCID 178506823, compound

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Reaction Steps

By the method described in Example 7 using n-butyl lithium solution (9% w/v, 25 ml, 0.034 mol), and 3,4-dimethyl-5,6,7,8-tetrahydroquinoline-(5.65 g, 0.034 mol) the title compound is prepared and converted to methyl 3,4-dimethyl-5,6,7,8-tetrahydroquinoline-8-carboxylate which is then converted to the corresponding 8-thioamide by the procedure of U.S. Ser. No. 460,265.

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