HCID 131711571, compound → HCID 13968094, compound

Participants

Reaction Steps

1.1 g of Z-Val-Gly-Ala-Pro-NH2 are dissolved in 50 ml of 80 % strength methanol and the solution is hydrogenated in the presence of 0.3 g of palladium on charcoal (10 % Pd). When the hydrogen uptake has ended the catalyst is filtered off, the solution evaporated and the residue dried in a high vacuum at 35° C. bath temperature. Hereupon the tetrapeptide H-Val-Gly-Ala-Pro-NH 2 is obtained as a colourless substance, Rf-Value = 0.20 (silica gel plates, system chloroform-methanol = 1:1).

Provenance & Evidence