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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 971855Generated: October 30, 2026

Acetyl chloride → HCID 54180656, compound

https://huagongshe.com/reaction/971855

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantTriethylamineHCID 8471—
Reactant2-(4-Phenoxyphenyl)pyrrolidineHCID 45789703—
SolventDiethyl EtherHCID 3283—
ProductHCID 54180656HCID 54180656—

Reaction Steps

To a solution of 10 parts of 2-(4-phenoxyphenyl) pyrrolidine in 200 parts of anhydrous ether and 4.2 parts of triethylamine, there was added a solution of 3.3 parts of acetyl chloride in 30 parts of ether. The reflux was maintained for one hour, then the reaction mixture was filtered off on cooling and the filtrate was distilled. There were obtained 13 parts of 1-acetyl-2-(4-phenoxyphenyl) pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04161529
Source datasetuspto-grants-1979_07
ORD IDord-b2b2ae106a2141feaa536b7007d7f4ab
Source noteuspto-grants-1979_07