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HRID971918

反应详情

EQUATION

反应方程式

HRID 971918 的结构方程式

REACTANTS

反应物

3
结构：COc1ccc2c3c1O[C@H]1C(=O)CC[C@@]4(O)[C@@H](C2)N(CC2CC2)CC[C@]314
HCID5487695

17-(Cyclopropylmethyl)-14-hydroxy-3-methoxy-4,5-epoxymorphinan-6-one

C21H25NO4

结构：COc1ccc2c(c1)[C@]13CCN(CC4CCC4)[C@H](C2)[C@]1(O)CCC(=O)C3
HCID57257006

未命名化合物

结构：COc1ccc2c(c1)[C@@]13CCCC[C@@]1(O)[C@@H](C2)N(CC1CC1)CC3
HCID70587809

未命名化合物

PRODUCTS

生成物

3
结构：O=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)c5c4[C@@]2(CCN3CC2CC2)[C@H]1O5
HCID5360515

Naltrexone

C20H23NO4

结构：Oc1ccc2c(c1)[C@@]13CCCC[C@@]1(O)[C@@H](C2)N(CC1CC1)CC3
HCID5361090

Oxilorphan

C20H27NO2

结构：O=C1CC[C@@]2(O)[C@H]3Cc4ccc(O)cc4[C@@]2(CCN3CC2CCC2)C1
HCID57088644

未命名化合物

PROCEDURE

实验过程

In accordance with the above procedure, but starting, in place of N-cyclobutylmethylnoroxycodone, with N-cyclopropylmethylnoroxycodone (6a), N-ethylnoroxycodone (6c), N-cyclopropylmethyl-3-methoxy-14-hydroxymorphinan (6e), or N-cyclobutylmethyl-3-methoxy-14-hydroxy-6-oxomorphinan (6f), there is obtained the corresponding N-cyclopropylmethylnoroxymorphone (7a), N-ethylnoroxymorphone (7c), N-cyclopropylmethyl-3,14-dihydroxymorphinan (7e) or N-cyclobutylmethyl-3,14-dihydroxy-6-oxomorphinan (7f).