HRID97202

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

4 次

HCID23938

Palladium

HCID28179

Fluoride

F-

HCID31275

1,4-Dioxane

C4H8O2

HCID104967

Cesium(1+)

Cs+

HCID2783171

2-Bromo-5-fluoropyridine

C5H3BrFN

HCID59676752

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)C1(Cc2ccc(-c3ccc(F)cn3)cc2)CCC(=O)N1

HCID66705606

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8af55b6581bf4f6f824ee23d7abb9a95
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (2/10)

反应 SMILES

[Br:1][c:2]1[cH:3][cH:4][c:5]([CH2:6][C:7]2([C:13](=[O:14])[O:15][CH2:16][CH3:17])[NH:8][C:9](=[O:12])[CH2:10][CH2:11]2)[cH:18][cH:19]1.[Br:20][c:21]1[n:22][cH:23][c:24]([F:27])[cH:25][cH:26]1.[CH2:30]1[O:31][CH2:32][CH2:33][O:34][CH2:35]1.[Cs+:29].[F-:28].[Pd:112].[c:36]1([P:37]([c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[cH:50][cH:51][cH:52][cH:53][cH:54]1.[c:55]1([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[cH:69][cH:70][cH:71][cH:72][cH:73]1.[c:74]1([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[cH:88][cH:89][cH:90][cH:91][cH:92]1.[c:93]1([P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)[c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[cH:107][cH:108][cH:109][cH:110][cH:111]1>>[c:2]1(-[c:21]2[n:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[cH:3][cH:4][c:5]([CH2:6][C:7]2([C:13](=[O:14])[O:15][CH2:16][CH3:17])[NH:8][C:9](=[O:12])[CH2:10][CH2:11]2)[cH:18][cH:19]1