HRID972021

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID14797

Potassium hydroxide

HKO

HCID25795

2,2′,2′′-[1,2,3-Propanetriyltris(oxymethylene)]tris[oxirane]

C12H20O6

HCID20481853

7,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

C12H21N3O2

PRODUCTS

生成物

结构：CN1C(C)(C)CC2(CC1(C)C)NC(=O)N(CC(O)COCC(COCC(O)CN1C(=O)NC3(CC(C)(C)N(C)C(C)(C)C3)C1=O)OCC(O)CN1C(=O)NC3(CC(C)(C)N(C)C(C)(C)C3)C1=O)C2=O

HCID131711585

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

PROCEDURE

实验过程

12.0 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]-decane-2,4-dione, 4.1 g of glycerol tris(2,3-epoxypropyl)ether and 1.1 g of potassium hydroxide were reacted in 80 ml of methanol, following substantially the same procedure as in Example 1. The desired Compound No. 177 was obtained in the form of a white powder, having an Rf value of 0.45 on thin-layer chromatography on silica gel using a 4:4:4:1:1 by volume mixture of benzene, ethyl acetate, chloroform, methanol and triethylamine as developing solvent.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-92d226cb0e284e6eb5648e6b1e540e68
来源数据集: uspto-grants-1979_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04162246
来源说明: uspto-grants-1979_07

反应 SMILES

[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:35][CH:19]1[CH2:20][O:21][CH2:22][CH:23]([CH2:29][O:30][CH2:31][CH:32]1[O:34][CH2:33]1)[O:24][CH2:25][CH:26]1[O:28][CH2:27]1.[OH-:36].[K+]>CO>[OH:18][CH:19]([CH2:35][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][CH2:22][CH:23]([CH2:29][O:30][CH2:31][CH:32]([OH:34])[CH2:33][N:6]1[C:5](=[O:36])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[O:24][CH2:25][CH:26]([OH:28])[CH2:27][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9]