1-Isocyanato-4-methoxybenzene → HCID 20396659, compound

HRID 972126Notes

Reaction equation

HRID 972126 reaction equation
[CH3:1][O:2][CH:3]([O:13][CH3:14])[CH2:4][O:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[CH:8][CH:7]=1.[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([N:23]=[C:24]=[O:25])=[CH:19][CH:18]=1.[N-]=C=O>C1C=CC=CC=1.C(N(CC)CC)C>[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([NH:23][C:24](=[O:25])[O:12][C:9]2[CH:10]=[CH:11][C:6]([O:5][CH2:4][CH:3]([O:2][CH3:1])[O:13][CH3:14])=[CH:7][CH:8]=2)=[CH:19][CH:18]=1

Participants

6

Reactant 3

HCID 794431-Isocyanato-4-methoxybenzeneHCID 105034IsocyanateHCID 20396656HCID 20396656, compound

Product 1

HCID 20396659HCID 20396659, compound

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 241BenzeneSolvent

Procedure

4-(2,2-Dimethoxyethoxy)phenol (0.05 mole) dissolved in benzene (10 ml) is charged into a glass reaction flask equipped with a mechanical stirrer. 4-Methoxyphenyl isocyanate (0.06 mole) and triethylamine (3 drops) are then added, and the resulting mixture is stirred at room temperature for a period of about 6 hours. The mixture is then stripped of solvent and unreacted isocyanate to yield the desired product O-[4-(2,2-dimethoxyethoxy)phenyl] N-4-methoxyphenylcarbamate as the residue.

Workup

  1. additionis charged into a glass reaction flask
  2. customequipped with a mechanical stirrer

Sources & evidence

ORD record
ord-d7e252c49f04405f8399e30daf5291c7
Source dataset
uspto-grants-1979_07
Patent number
US04163112

Reaction notes

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