3-Nitrophenyl isocyanate → HCID 20396710, compound

HRID 972128Notes

Reaction equation

HRID 972128 reaction equation
[CH3:1][O:2][CH:3]([O:13][CH3:14])[CH2:4][S:5][C:6]1[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=1.[N+:15]([C:18]1[CH:19]=[C:20]([N:24]=[C:25]=[O:26])[CH:21]=[CH:22][CH:23]=1)([O-:17])=[O:16].[N-]=C=O>C1C=CC=CC=1.C(N(CC)CC)C>[N+:15]([C:18]1[CH:19]=[C:20]([NH:24][C:25](=[O:26])[O:12][C:8]2[CH:9]=[CH:10][CH:11]=[C:6]([S:5][CH2:4][CH:3]([O:2][CH3:1])[O:13][CH3:14])[CH:7]=2)[CH:21]=[CH:22][CH:23]=1)([O-:17])=[O:16]

Participants

6

Reactant 3

HCID 768353-Nitrophenyl isocyanateHCID 105034IsocyanateHCID 203966733-(2,2-Dimethoxyethylthio)phenol

Product 1

HCID 20396710HCID 20396710, compound

Reagents, catalysts & solvents 2

HCID 8471TriethylamineCatalystHCID 241BenzeneSolvent

Procedure

3-(2,2-Dimethoxyethylthio)phenol (0.05 mole) dissolved in benzene (10 ml) is charged into a glass reaction flask equipped with a mechanical stirrer. 3-Nitrophenyl isocyanate (0.06 mole) and triethylamine (3 drops) are then added and the resulting mixture is stirred at room temperature for a period of about 6 hours. The mixture is then stripped of solvent and unreacted isocyanate to yield the desired product O-[3-(2,2-dimethoxyethylthio) phenyl] N-3-nitrophenylcarbamate as the residue.

Workup

  1. additionis charged into a glass reaction flask
  2. customequipped with a mechanical stirrer

Sources & evidence

ORD record
ord-3bd8df35866f4827aae1a20d095dfa18
Source dataset
uspto-grants-1979_07
Patent number
US04163112

Reaction notes

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