Dichloromethane → 2-(N-tert-butylsulfamoyl)-N-(2-carbamoylbiphenyl-3-yl)thiazole-4-carboxamide

HRID 97215Notes

Reaction equation

HRID 97215 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][cH:11][c:12]([C:14](=[O:15])[OH:16])[n:13]1.[CH:41]([N:42]([CH2:43][CH3:44])[CH:45]([CH3:46])[CH3:47])([CH3:48])[CH3:49].[Cl:66][CH2:67][Cl:68].[NH2:50][c:51]1[c:52]([C:63](=[O:64])[NH2:65])[c:53](-[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:54][cH:55][cH:56]1.[P-:17]([F:18])([F:19])([F:20])([F:21])([F:22])[F:23].[n:24]1([O:25][C:26]([N:27]([CH3:28])[CH3:29])=[N+:30]([CH3:31])[CH3:32])[c:33]2[n:34][cH:35][cH:36][cH:37][c:38]2[n:39][n:40]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][cH:11][c:12]([C:14](=[O:16])[NH:50][c:51]2[c:52]([C:63](=[O:64])[NH2:65])[c:53](-[c:57]3[cH:58][cH:59][cH:60][cH:61][cH:62]3)[cH:54][cH:55][cH:56]2)[n:13]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 669655723-Aminobiphenyl-2-carboxamideHCID 670559302-(N-tert-butylsulfamoyl)thiazole-4-carboxylic acid

Product 1

HCID 670559462-(N-tert-butylsulfamoyl)-N-(2-carbamoylbiphenyl-3-yl)thiazole-4-carboxamide

Sources & evidence

ORD record
ord-63109adae0e04f4b8989eeae8b7f9269
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…