HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-ethoxycarbonylpropanoyl)-L-hydroxyproline → 1-(2-carboxypropanoyl)-L-hydroxyproline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-ethoxycarbonylpropanoyl)-L-hydroxyproline | HCID 70609794 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 1-(2-carboxypropanoyl)-L-hydroxyproline | HCID 70610582 | — |
Reaction Steps
1-(2-Ethoxycarbonylpropanoyl)-L-hydroxyproline is dissolved in a mixture of methanol (20 ml.) and N sodium hydroxide (20 ml.). After 6 hours the solvent is concentrated in vacuo to half volume and applied to a column of resin Dowex 50 (50 ml.) and eluted with water to obtain 1-(2-carboxypropanoyl)-L-hydroxyproline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04052511 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-3d13164528ba4ea9a86173b553e3723d |
| Source note | uspto-grants-1977_10 |