Cyclohexyl isocyanate → HCID 178485086, compound

HRID 972377Notes

Reaction equation

HRID 972377 reaction equation
[CH3:1][N:2]([CH3:7])[C:3]([NH2:6])=[N:4][CH3:5].[CH:8]1([N:14]=[C:15]=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>C1(C)C=CC=CC=1>[CH:8]1([NH:14][C:15]([N:6]=[C:3]([NH:4][CH3:5])[N:2]([CH3:7])[CH3:1])=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 18502Cyclohexyl isocyanateHCID 141619N,N,N′-Trimethylguanidine

Product 1

HCID 178485086HCID 178485086, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To 60.6 parts by weight of 1,1,2-trimethylguanidine in 600 parts by volume of toluene are added dropwise with cooling 75 parts by weight of cyclohexyl isocyanate. After evaporation of the solvent in vacuo, the product is recrystallized from acetonitrile to yield 2-cyclohexylcarbamoyl-1,1,3-trimethylguanidine, m.p. 121°-124° C.

Workup

  1. customAfter evaporation of the solvent in vacuo
  2. customthe product is recrystallized from acetonitrile

Sources & evidence

ORD record
ord-bd00a2121e2842f294c6457713ad36d7
Source dataset
uspto-grants-1977_10
Patent number
US04053299

Reaction notes

Loading…