Hydrochloric Acid → HCID 21404683, compound

HRID 972499Notes

Reaction equation

HRID 972499 reaction equation
[N+:1]([C:4]1[N:8]([CH2:9][CH2:10][O:11]C(=O)C)[C:7]([C:15]2[NH:16][C:17]3[CH:23]=[CH:22][CH:21]=[CH:20][C:18]=3[N:19]=2)=[N:6][CH:5]=1)([O-:3])=[O:2].Cl>C(O)C>[N+:1]([C:4]1[N:8]([CH2:9][CH2:10][OH:11])[C:7]([C:15]2[NH:19][C:18]3[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=3[N:16]=2)=[N:6][CH:5]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21404673HCID 21404673, compound

Product 1

HCID 21404683HCID 21404683, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3.5 mg. of 2-[5-nitro-1-(2-acetoxyethyl)-2-imidazolyl]-benzimidazole are boiled for 1 hour in 8 ml. of ethanol with 4 ml. of concentrated aqueous hydrochloric acid. After concentrating the reaction mixture to dryness, the residue is digested with methanol. After vacuum-filtering, 226 mg. of 2-[5-nitro-1-(2-hydroxyethyl)-2-imidazolyl]-benzimidazole is obtained, m.p. 217°-219° C.

Workup

  1. concentrationAfter concentrating the reaction mixture to dryness
  2. filtrationAfter vacuum-filtering

Sources & evidence

ORD record
ord-f99164a5106c4be287b5928089ba705f
Source dataset
uspto-grants-1977_10
Patent number
US04053472

Reaction notes

Loading…