HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → N-(4,5,6,7-Tetrahydro-1-benzothiophen-4-yl)urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Benzoyl-3-(4,5,6,7-tetrahydrobenzo-[b]thien-4-yl)urea | HCID 13037006 | — |
| Product | N-(4,5,6,7-Tetrahydro-1-benzothiophen-4-yl)urea | HCID 13036998 | — |
Reaction Steps
A mixture of 1-benzoyl-3-(4,5,6,7-tetrahydrobenzo-[b]thien-4-yl) urea and 2N aqueous sodium hydroxide solution (5ml) is stirred at reflux for 2.5 hours. The mixture is cooled in ice, the product is collected and washed with water to afford 0.58 g of title compound, m.p. 203° to 207° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04053484 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-14391dd763914b96a03eb547db6e1b88 |
| Source note | uspto-grants-1977_10 |