Methylhydrazine → HCID 131710936, compound

HRID 972662Notes

Reaction equation

HRID 972662 reaction equation
[ClH:1].[CH3:2][N:3]([CH3:25])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]([CH:14]=[C:15]2[CH2:23][C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[C:16]2=O)[CH:11]=[CH:12][CH:13]=1.[CH3:26][NH:27][NH2:28]>CO>[ClH:1].[CH3:2][N:3]([CH3:25])[CH2:4][CH2:5][CH2:6][O:7][C:8]1[CH:9]=[C:10]([CH:14]2[N:27]([CH3:26])[N:28]=[C:16]3[C:17]4[C:22]([CH2:23][CH:15]23)=[CH:21][CH:20]=[CH:19][CH:18]=4)[CH:11]=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 70631851HCID 70631851, compound

Product 1

HCID 131710936HCID 131710936, compoundYield 10.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A stirred solution of 8.6 g (0.024 mole) of 2-[[3-[3-(dimethylamino)propoxy]phenyl]methylene]-2,3-dihydro-1H-inden-1-one hydrochloride from part B and 1.3 g (0.028 mole) of methyl hydrazine in 50 ml of methanol is heated at reflux for 2 hours. After cooling, the solvent is evaporated to give 1.0 g of an amber oily residue.

Workup

  1. temperatureat reflux for 2 hours
  2. temperatureAfter cooling
  3. customthe solvent is evaporated

Sources & evidence

ORD record
ord-f01056cc0e8147c7b0418e693cb1ed3e
Source dataset
uspto-grants-1977_10
Patent number
US04053514

Reaction notes

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