Methylamine → HCID 68122860, compound

HRID 972729Notes

Reaction equation

Cl[CH:2]([CH3:27])[C:3]([NH:5][C:6]1[C:22]([O:23][CH3:24])=[C:21]([O:25][CH3:26])[CH:20]=[CH:19][C:7]=1[CH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][N:10]=1)=[O:4].[CH3:28][NH2:29]>>[CH3:28][NH:29][CH:2]([CH3:27])[C:3]([NH:5][C:6]1[C:22]([O:23][CH3:24])=[C:21]([O:25][CH3:26])[CH:20]=[CH:19][C:7]=1[CH2:8][C:9]1[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][N:10]=1)=[O:4]

Participants

Reactant 2

HCID 6329Methylamine

HCID 12369646HCID 12369646, compound

Product 1

HCID 68122860HCID 68122860, compound

Procedure

Following the procedure of Example 1, but reacting 1-(2-[2-chloro-propionyl] amino-3,4-dimethoxybenzyl) isoquinoline with methylamine, there is obtained 1-(2-[2-methylamino-propionyl] amino-3,4-dimethoxybenzyl)isoquinoline.

Sources & evidence

ORD record: ord-d86da06c09a34ac48d9a34a56a6679ef
Source dataset: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04053603

Reaction notes

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