Hydrazine hydrate (1:1) → HCID 20309456, compound

Participants

Reaction Steps

A stirred mixture of 6-[2-(3-t-butylamino-2-hydroxypropoxy)-4-methoxyphenyl]-3-methoxypyridazine (0.36 g, 0.001 mole) and hydrazine hydrate (8 ml) was heated under reflux for 2 hours. Excess of hydrazine hydrate was removed under reduced pressure and 6-[2-(3-t-butylamino-2-hydroxypropoxy)-4-methoxyphenyl]-3-hydrazino pyridazine was isolated by crystallisation from ethanol-ether

Provenance & Evidence