Tert-Butylamine → HCID 21405185, compound

HRID 972783Notes

Reaction equation

HRID 972783 reaction equation
[C:1]([O:5][C:6]([NH:8][NH:9][C:10]1[N:15]=[N:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[CH:18][C:17]=2[O:24][CH2:25][CH:26]2[O:28][CH2:27]2)=[CH:12][CH:11]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:29]([NH2:33])([CH3:32])([CH3:31])[CH3:30]>CO>[C:29]([NH:33][CH2:27][CH:26]([OH:28])[CH2:25][O:24][C:17]1[CH:18]=[C:19]([O:22][CH3:23])[CH:20]=[CH:21][C:16]=1[C:13]1[N:14]=[N:15][C:10]([NH:9][NH:8][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])=[CH:11][CH:12]=1)([CH3:32])([CH3:31])[CH3:30]

Participants

4

Reactant 2

HCID 6385Tert-ButylamineHCID 21405178HCID 21405178, compound

Product 1

HCID 21405185HCID 21405185, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of 6-(2-t-butyloxycarbonylhydrazino)-3-[2-(2,3-epoxypropoxy)-4-methoxyphenyl]pyridazine and t-butylamine in methanol was allowed to stand at room temperature for 48 hours. Evaporation of the reaction mixture gave 3-[2-(3-t-butylamino-2-hydroxypropoxy)-4-methoxyphenyl]-6-(2-t-butyloxycarbonylhydrazino)pyridazine.

Workup

  1. customEvaporation of the reaction mixture

Sources & evidence

ORD record
ord-532b1028d8c94805b1dfc650b62634b2
Source dataset
uspto-grants-1977_10
Patent number
US04053601

Reaction notes

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