Hydrazine hydrate (1:1) → HCID 135727403, compound

HRID 972786Notes

Reaction equation

HRID 972786 reaction equation
[C:1]([NH:5][CH2:6][CH:7]([OH:24])[CH2:8][O:9][C:10]1[CH:15]=[C:14]([OH:16])[CH:13]=[CH:12][C:11]=1[C:17]1[N:18]=[N:19][C:20](Cl)=[CH:21][CH:22]=1)([CH3:4])([CH3:3])[CH3:2].O.[NH2:26][NH2:27]>>[C:1]([NH:5][CH2:6][CH:7]([OH:24])[CH2:8][O:9][C:10]1[CH:15]=[C:14]([OH:16])[CH:13]=[CH:12][C:11]=1[C:17]1[N:18]=[N:19][C:20]([NH:26][NH2:27])=[CH:21][CH:22]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 135731738HCID 135731738, compound

Product 1

HCID 135727403HCID 135727403, compound

Procedure

3-[2-(3-t-Butylamino-2-hydroxypropoxy)-4-hydroxyphenyl]-6-chloropyridazine was reacted with hydrazine hydrate under similar conditions to those described in Example 7b(iii) to give the title compound.

Sources & evidence

ORD record
ord-c0ef3677ff8742109d30649e89a275e6
Source dataset
uspto-grants-1977_10
Patent number
US04053601

Reaction notes

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