Hydrazine hydrate (1:1) → HCID 21405193, compound

HRID 972799Notes

Reaction equation

HRID 972799 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:15][CH2:16][CH:17](O)[CH2:18][NH:19][C:20]([CH3:23])([CH3:22])[CH3:21])=[C:6]([C:8]2[CH:9]=[CH:10][C:11](=S)[NH:12][N:13]=2)[CH:7]=1.[OH2:25].[NH2:26][NH2:27]>>[NH2:1][C:2]1[CH:3]=[CH:4][C:5]([O:15][CH2:16][CH2:17][CH:18]([NH:19][C:20]([CH3:23])([CH3:22])[CH3:21])[OH:25])=[C:6]([C:8]2[N:13]=[N:12][C:11]([NH:26][NH2:27])=[CH:10][CH:9]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20309493HCID 20309493, compound

Product 1

HCID 21405193HCID 21405193, compound

Procedure

Reaction of 6-[5-amino-2-(3-t-butylamino-2-hydroxypropoxy)phenyl]-3(2H)-pyridazinethione with hydrazine hydrate under similar conditions to those described in Example 2(vi) gave the title compound.

Sources & evidence

ORD record
ord-8e9188151a424dc999eb5184c7b9d3e1
Source dataset
uspto-grants-1977_10
Patent number
US04053601

Reaction notes

Loading…