Hydrazine hydrate (1:1) → HCID 21405172, compound

HRID 972801Notes

Reaction equation

HRID 972801 reaction equation
[C:1]([NH:4][C:5]1[CH:6]=[CH:7][C:8]([O:18][CH2:19][CH:20]([OH:27])[CH2:21][NH:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[C:9]([C:11]2[CH:12]=[CH:13][C:14](=S)[NH:15][N:16]=2)[CH:10]=1)(=[O:3])[CH3:2].O.[NH2:29][NH2:30]>C(O)C>[C:1]([NH:4][C:5]1[CH:6]=[CH:7][C:8]([O:18][CH2:19][CH:20]([OH:27])[CH2:21][NH:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[C:9]([C:11]2[N:16]=[N:15][C:14]([NH:29][NH2:30])=[CH:13][CH:12]=2)[CH:10]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 20309478HCID 20309478, compound

Product 1

HCID 21405172HCID 21405172, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Reaction of 6-[5-acetamido-2-(3-t-butylamino-2-hydroxypropoxy)phenyl]-3(2H)-pyridazinethione with hydrazine hydrate in boiling ethanol followed by evaporation of the reaction mixture under reduced pressure gave the title compound.

Workup

  1. customfollowed by evaporation of the reaction mixture under reduced pressure

Sources & evidence

ORD record
ord-efde699257164405aa9a113e28d16843
Source dataset
uspto-grants-1977_10
Patent number
US04053601

Reaction notes

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