HRID972808

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6811

Phthalic anhydride

C8H4O3

HCID415852

1-Benzyl-4-piperidinylamine

C12H18N2

PRODUCTS

生成物

结构：O=C1c2ccccc2C(=O)N1C1CCN(Cc2ccccc2)CC1

HCID2826246

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID887

Methanol

CH4O

CONDITIONS

反应条件

温度: 150 °C

PROCEDURE

实验过程

16.8 Grams of phthalic anhydride and 21.6 grams of 4-amino-1-benzyl-piperidine were stirred together while they were being heated in an oil bath at 150° C. for 30 minutes. On cooling, the resulting glassy solid was heated with 400 milliliters of methanol to give 26.5 grams of 1-benzyl-4-phthalimidopiperidine. Melting point: 154°-7° C.

WORKUP

后处理

temperatureOn cooling