HCID 21405556, compound → HCID 21405566, compound

Participants

Reaction Steps

2.8 Grams of 1-ethyl-3-(4-nitrophthalimido)piperidine were dissolved in 50 milliliters of hot glacial acetic acid and were hydrogenated at 50° C. and 50 p.s.i. in the presence of 0.1 grams of 5% palladium-on-charcoal catalyst until the theoretical amount of hydrogen was taken up. The hot solution was filtered and the mixture cooled and the solid formed was filtered and dried to give 1.06 grams of the title compound in the form of the monohydrochloride.

Provenance & Evidence