HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → 1-(2-thienylmethyl)piperidin-4-amine(SALTDATA: 2HCl)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | Aluminum | HCID 5359268 | — |
| Reactant | 41661-54-5 | HCID 18001837 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 1-(2-thienylmethyl)piperidin-4-amine(SALTDATA: 2HCl) | HCID 17221638 | — |
Reaction Steps
N-(2-Thienylmethyl)-4-piperidone is reacted with hydroxylamine, followed by nickel, aluminium alloy in 30% sodium hydroxide solution, in a similar manner to that described in Example 19 to give 4-amino-N-(2-thienylmethyl)piperidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04053615 |
| Source dataset | uspto-grants-1977_10 |
| ORD ID | ord-9faeccc2585945bda1439939a089684e |
| Source note | uspto-grants-1977_10 |