Benzyl Chloride → HCID 20264049, compound

HRID 972869Notes

Reaction equation

HRID 972869 reaction equation
[OH:1][C:2]1[C:3]([CH3:12])=[N:4][CH:5]=[C:6]([CH:10]=[CH2:11])[C:7]=1[CH2:8][OH:9].C(=O)([O-])[O-].[K+].[K+].[CH2:19](Cl)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>CC(C)=O>[CH3:12][C:3]1[C:2]([O:1][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:7]([CH2:8][OH:9])[C:6]([CH:10]=[CH2:11])=[CH:5][N:4]=1

Participants

5

Reactant 3

HCID 7503Benzyl ChlorideHCID 11430Potassium CarbonateHCID 13066945HCID 13066945, compound

Product 1

HCID 20264049HCID 20264049, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a mixture of 0.1 mole 3-hydroxy-4-hydroxymethyl-2-methyl-5-vinylpyridine in 500 ml. of acetone and 25 gm. potassium carbonate is added 0.11 mole of benzyl chloride. The reaction mixture is stirred overnight, filtered, and the acetone removed in vacuo to yield 2-methyl-3-benzyloxy-4-hydroxymethyl-5-vinylpyridine.

Workup

  1. filtrationfiltered
  2. customthe acetone removed in vacuo

Sources & evidence

ORD record
ord-fad941027625461695d0a3f9f824d944
Source dataset
uspto-grants-1977_10
Patent number
US04053606

Reaction notes

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