Ethanolamine → 3-Methyl-4-phenylbut-3-enoic acid

HRID 972883Notes

Reaction equation

HRID 972883 reaction equation
[CH3:1][C:2](=[CH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:3][C:4](Cl)=[O:5].CC1CCC([OH:42])C/C/1=C/C=C1\CCCC2(C)C(C(/C=C/C(C(C)C)C)C)CCC\12.C(CN)O>C1C=CC=CC=1>[CH3:1][C:2](=[CH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH2:3][C:4]([OH:42])=[O:5]

Participants

5

Reactant 3

HCID 700EthanolamineHCID 5281010(3Z)-3-[(2E)-2-[1-[(E)-5,6-dimethylhept-3-en-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylcyclohexan-1-olHCID 54476880HCID 54476880, compound

Product 1

HCID 2934493-Methyl-4-phenylbut-3-enoic acid

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Conditions

Temperature
20 °C

Procedure

194 g of 3-methyl-4-phenyl-3-butenoic acid chloride (1 mole), dissolved into 500 ml benzene, are treated at-10° C with 183 g of monoethanolamine (3 moles). The mixture is stirred at 20° C for 3 hours.

Sources & evidence

ORD record
ord-f85dc8370cbf44aea654c5a22599f515
Source dataset
uspto-grants-1977_10
Patent number
US04053635

Reaction notes

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