L-Phenylalanine → HCID 22859218, compound

HRID 972900Notes

Reaction equation

N[C@H](C(O)=O)CC1C=CC=CC=1.N[C@H](C(O)=O)C(C)C.C([S:24][CH2:25][CH:26]([CH3:41])[C:27]([NH:29][C@H:30]([C:38]([OH:40])=[O:39])[CH2:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)=[O:28])(=O)C>>[SH:24][CH2:25][CH:26]([CH3:41])[C:27]([NH:29][C@H:30]([C:38]([OH:40])=[O:39])[CH2:31][C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)=[O:28]

Participants

Reactant 3

HCID 6140L-Phenylalanine

HCID 6287L-Valine

HCID 22859211HCID 22859211, compound

Product 1

HCID 22859218HCID 22859218, compound

Procedure

By substituting L-phenylalanine for the L-valine in the procedure of Example 22, and then treating the product by the procedure of Example 23, N-(3-actylthio-2-methylpropanoyl)-L-phenylalanine and N-(3-mercapto-2-methylpropanoyl)-L-phenylaline are obtained.

Workup

customare obtained

Sources & evidence

ORD record: ord-e471e066eb8e44ed9c7cb83da9a0460b
Source dataset: uspto-grants-1977_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04053651

Reaction notes

Loading…