反应详情

A mixture of 3.0 g. of 3,5-dinitro-4-(dipropylamino)benzaldehyde, 2.0 ml. of 1,2-propanediol, 75 ml. of benzene, and a small amount of p-toluenesulfonic acid was refluxed for about 4 hours, using a Dean-Stark trap to collect the evolved water. The reaction product mixture was cooled and extracted successively with saturated aqueous sodium bicarbonate solution, and brine, and then dried. The drying agent was filtered off and the benzene solution passed through an aluminum oxide column. The eluate was collected and evaporated. A total of 2.2 g. of 4-(4-methyl-1,3-dioxolan-2-yl)-2,6-dinitro-N,N-dipropylaniline was isolated as an oil.

1. additionA mixture of 3.0 g
2. customto collect the evolved water
3. temperatureThe reaction product mixture was cooled
4. extractionextracted successively with saturated aqueous sodium bicarbonate solution, and brine
5. customdried
6. filtrationThe drying agent was filtered off
7. customThe eluate was collected
8. customevaporated