HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 131725893, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3-(2-Bromo-phenyl)-1-methyl-7-(4-methyl-3-oxo-3,4-dihydro-2h-benzo[1,4]thiazin-7-ylamino)-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one | HCID 10481466 | — |
| Reactant | Potassium hydroxy sulfite | HCID 23707502 | — |
| Product | HCID 131725893 | HCID 131725893 | — |
Reaction Steps
100 mg of the compound from example 9 and 108 mg oxone were stirred in 2 ml MeOH at room temperature for 17 hrs. The mixture was filtered and the residue washed with THF. The combined filtrates were concentrated and purified by preparative HPLC-MS to yield 10 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07091345B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-3217fe884c024c1793d25f2ce03d4619 |
| Source note | uspto-grants-2006_08 |