m-Chloroperbenzoic acid → HCID 21402171, compound

HRID 973243Notes

Reaction equation

HRID 973243 reaction equation
ClC1C=CC=C(C(OO)=[O:9])C=1.[Cl:12][CH:13]([C:20]1[CH:25]=[CH:24][C:23]([S:26][CH3:27])=[CH:22][CH:21]=1)[CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1>C(Cl)(Cl)Cl>[Cl:12][CH:13]([C:20]1[CH:25]=[CH:24][C:23]([S:26]([CH3:27])=[O:9])=[CH:22][CH:21]=1)[CH2:14][N:15]1[CH:19]=[CH:18][N:17]=[CH:16]1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 21402265HCID 21402265, compound

Product 1

HCID 21402171HCID 21402171, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent2×

Procedure

A solution of 85% m-chloroperbenzoic acid in chloroform (2 g/100 ml.) is added dropwise, over a period of one hour, to a stirred solution of 2.53 g. of 1-[β-chloro-4-methylthiophenethyl]imidazole in 150 ml. of chloroform at 0° C. After 6 hours, the resultant solution is washed with aqueous potassium carbonate and with water. The organic phase is separated and dried over magnesium sulfate. Evaporation of the solvent yields 1-[β-chloro-4-methylsulfinylphenethyl]imidazole.

Workup

  1. customat 0° C
  2. washthe resultant solution is washed with aqueous potassium carbonate and with water
  3. customThe organic phase is separated
  4. dry with materialdried over magnesium sulfate
  5. customEvaporation of the solvent

Sources & evidence

ORD record
ord-a0d7cb319aa04c588e368430a882e422
Source dataset
uspto-grants-1977_10
Patent number
US04055652

Reaction notes

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