HCID 13384229, compound → HCID 13384230, compound

Participants

Reaction Steps

The above process is repeated except that the ethyl 2-(4-chlorophenoxy)-3,3,3-trifluoro-2-trifluoromethylpropionate is replaced by ethyl 2-phenoxy-3,3,3-trifluoro-2-trifluoromethylpropionate (13 g.) and the residue obtained by evaporation of the ethereal extract is purified by distillation at 10-3 mm. pressure, crystallisation from petrol (b.p. 30°-40° C.) at -65° C. and redistillation to give 2-phenoxy-3,3,3-trifluoro-2-trifluoromethylpropionic acid, b.p. 68°-70° C, at 10-3 mm., m.p. 6°-8° c. (8 g.).

Provenance & Evidence