反应详情

温度

60 °C

A mixture of 8-carbamoyl-12-hydroxyheptadecanoic acid (8.2 g., 0.025 mole) (Example 1, Step F) and 97% formic acid (10 ml.) is heated at 60° C. for 24 hours. The mixture is cooled, dissolved in 100 ml. ether, washed with 3 portions of water and dried over sodium sulfate. Evaporation of the ether leaves the product 8-carbamoyl-12-formyloxyheptadecanoic acid as a slightly yellowish viscous oil.

1. temperatureThe mixture is cooled
2. dissolutiondissolved in 100 ml
3. washether, washed with 3 portions of water
4. dry with materialdried over sodium sulfate
5. customEvaporation of the ether