2-Chloro-5-nitrobenzaldehyde → HCID 54105706, compound

HRID 973371Notes

Reaction equation

HRID 973371 reaction equation
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([O-])=O.[Cl:10][C:11]1[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:12]=1C=O>N1C=CC=CC=1>[Cl:10][C:11]1[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:12]=1[CH:3]=[CH:2][C:1]([O:7][CH2:8][CH3:9])=[O:6]

Participants

4

Reactant 2

HCID 729332-Chloro-5-nitrobenzaldehydeHCID 3595298Propanedioic acid, monoethyl ester

Product 1

HCID 54105706HCID 54105706, compoundYield 31%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

33 g (250 millimoles) of monoethyl malonate and 27 g (150 millimoles) of 2-chloro-5-nitrobenzaldehyde in 100 ml of pyridine were reacted similarly to Example 1, and the mixture was worked up in a conventional manner. Yield: 31%, mp. 138°-140° C.

Sources & evidence

ORD record
ord-70eac62e3ed940cfa02eb2dbb241bab6
Source dataset
uspto-grants-1991_11
Patent number
US05062884

Reaction notes

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