Methylamine → HCID 15079190, compound

Participants

Reaction Conditions

Reaction Steps

In 50 ml of 40% methylamine solution in methanol was suspended 0.40 g of Compound 59 obtained in Example 61. The suspension was stirred at 60° C. for 3 hours and then concentrated. Thereafter, water was added to the residue, and the crystals precipitated were collected by filtration and dried to give 0.34 g (89%) of 4,5-dihydro-5-methyl-6-(4-methylamino-2-methylthioquinazolin-7-yl)-3(2H)-pyridazinone (Compound 60).

Provenance & Evidence