Triethylamine → HCID 15018153, compound

HRID 973511Notes

Reaction equation

HRID 973511 reaction equation
Cl.[N:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][N:10]([CH3:15])[S:11](Cl)(=[O:13])=[O:12].[CH3:16][O:17][C:18](=[O:31])[C@H:19]([C@@H:21]([CH3:30])[O:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[NH2:20].C(N(CC)CC)C>C(Cl)Cl>[CH3:16][O:17][C:18](=[O:31])[C@H:19]([C@@H:21]([CH3:30])[O:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[NH:20][S:11]([N:10]([CH2:9][CH2:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][N:2]=1)[CH3:15])(=[O:13])=[O:12]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 18647709HCID 18647709, compoundHCID 19989752HCID 19989752, compound

Product 1

HCID 15018153HCID 15018153, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To the resulting compound from Example 87 (1 mmol) and (O-benzyl)threonine methyl ester (1 mmol) in CH2Cl2 was added triethylamine (2.0 mmol). After 1 h the product was isolated as described in Example 80.

Workup

  1. customAfter 1 h the product was isolated

Sources & evidence

ORD record
ord-958690df7d6347da8fd53e5a51d282b8
Source dataset
uspto-grants-1991_11
Patent number
US05063208

Reaction notes

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