反应详情

18 g of potassium carbonate were added to 15 ml of 3-trifluoromethylphenol and 25 ml of 2-butanone with stirring and then 15.1 ml of 2-bromobutene in 70 ml of 2-butanone were added. The mixture was refluxed for 90 minutes, then stirred for 72 hours at ambient temperature. 300 ml of water were then added, followed by extraction with methylene chloride. The extracts were dried and concentrated to dryness to obtain 21.73 g of the expected product.

1. temperatureThe mixture was refluxed for 90 minutes
2. stirringstirred for 72 hours at ambient temperature
3. extractionfollowed by extraction with methylene chloride
4. customThe extracts were dried
5. concentrationconcentrated to dryness