Hydrochloric Acid → 2-[3-Methoxy-4-(phenylmethoxy)phenoxy]acetic acid

HRID 973742Notes

Reaction equation

HRID 973742 reaction equation
[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][C:12]([O:13][CH2:14][C:15]([O:17]CC)=[O:16])=[CH:11][C:10]=1[O:22][CH3:23])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[OH-].[Na+].Cl>>[CH2:1]([O:8][C:9]1[CH:21]=[CH:20][C:12]([O:13][CH2:14][C:15]([OH:17])=[O:16])=[CH:11][C:10]=1[O:22][CH3:23])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 53805257HCID 53805257, compound

Product 1

HCID 148787312-[3-Methoxy-4-(phenylmethoxy)phenoxy]acetic acidYield 97.7%

Procedure

Using the procedure of Step D of Example 16, 3.2 g of the product of Step B and 5 ml of 2N sodium hydroxide and then 5 ml of hydrochloric acid were reacted to obtain 2.85 g of the expected product.

Sources & evidence

ORD record
ord-10d2f0736a0f48d290556f10a78cdd0d
Source dataset
uspto-grants-1991_11
Patent number
US05064861

Reaction notes

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